StudyDrugSubjectsDesignResults
Gordon et al, 199317ClomipramineN = 305 weeksClomipramine > PLA
Age = 6 - 23CrossoverClomipramine > DMI
Dx = AUT19/28 (68%) responders
Remington et al, 200118ClomipramineN = 367 weeksClomipramine > PLA
HaloperidolAge = 10 - 36CrossoverClomipramine > Haloperidol
Dx = AUT
Sugie et al, 200521FluvoxamineN = 1812 weeksFluvoxamine 5/18 (28%) responders
Age = 3 - 8Crossover
Dx = AUT
McDougle et al, 199624FluvoxamineN = 3012 weeksFluvoxamine > PLA
Age = 18 - 53Parallel groups8/15 (53 %) responders
Dx = AUT
Hollander et aI, 200526FluoxetineN = 458 weeksFluoxetine > PLA repetitive behavior
Age = 5-16Crossover
Dx = AUT, ASP
Hollander et al, 201234FluoxetineN = 3712 weeksFluoxetine > PLA
Age = 18 - 60Parallel groups7/20 (35 %) responders
Dx = AUT
King et al, 200941CitalopramN = 14912 weeksCitalopram = PLA
Age = 5 -17Parallel groups
Dx = AUT
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